Participating Faculty
J. Adam Luckenbach
Name:J. Adam Luckenbach
Department:Northwest Fisheries Science Center
Credentials:2004 - Ph.D., North Carolina State University; Department of Zoology
Mailing Address:

Environmental Physiology Program
Northwest Fisheries Science Center
2725 Montlake Blvd. East
Seattle, WA 98112

Research Interests

Sex control and regulation of gametogenesis in fishes

Research Summary

Fish exhibit a high degree of plasticity in their modes of sex determination. My previous research focused on environmental sex determination in flounder, which exhibit a unique form of sex determination where both genetic and environmental factors, such as temperature, can influence genes expressed in the gonads and ultimately, the sex of the fish. Currently, I have several projects focusing on gonadal sex differentiation, sex control, and reproduction in sablefish (also known as black cod), a high-value marine species native to the Pacific Northwest. The overarching goals of these projects are to gain an understanding of the mechanisms that regulate sex differentiation and to develop novel approaches for controlling phenotypic sex of sablefish (e.g., induction of sterility and/or monosex production). From an applied perspective, production of reproductively sterile sablefish through non-transgenic approaches would mitigate escapement risks for cultured sablefish while also likely improving production and profits to growers. Other ongoing research focuses on the identification of ovarian genes regulated by follicle-stimulating hormone that may be critical to early stages of oocyte growth.

Research Publications

Luckenbach JA, Yamamoto Y, Guzmάn JM, P. Swanson. 2013. Identification of ovarian genes regulated by follicle-stimulating hormone (Fsh) in vitro during early secondary oocyte growth in coho salmon. Molecular and Cellular Endocrinology 3696:38-52.

Smith EK, Guzmάn JM, JA Luckenbach. 2013. Molecular cloning, characterization and sexually dimorphic expression of five major sex differentiation-related genes in a Scorpaeniform fish, sablefish (Anoplopoma fimbria). Comparative Biochemistry and Physiology Part B 165:125-137.

Guzmάn JM, JA Luckenbach and P. Swanson. 2013. Molecular characterization and quantification of sablefish (Anoplopoma fimbria) gonadotropins and their receptors: reproductive dysfunction in female captive broodstock. General and Comparative Endocrinology 193:37-47.

Metzger DC, JA Luckenbach, JT Dickey, BR Beckman. 2013. Development of a multiplex gene expression assay to identify potential growth rate indicators in salmon. General and Comparative Endocrinology 189:134-140.

Luckenbach JA, JT Dickey, P Swanson. 2011. Follicle-stimulating hormone regulation of ovarian transcripts for steroidogenesis-related proteins and cell survival, growth and differentiation factors in vitro during early secondary oocyte growth in coho salmon. General and Comparative Endocrinology 171:52-63

Luckenbach JA, RJ Borski, HV Daniels and J Godwin. 2009. Sex determination in flatfishes: mechanisms and environmental influences. Seminars in Cell And Developmental Biology 20:256-263.

Washington State University