Participating Faculty


Vanmathy Kasimanickam

Department:Veterinary Clinical Sciences
Credentials:2002 - DVM Canadian Veterinary Medical Association
Phone:509-335-6060; Lab: 509-335-6300
Mailing Address:

Veterinary Clinical Sciences

PO Box 646610
Pullman, WA 99164-6610

Research Interests

Male and Female Reproduction

Research Summary

Male Reproduction: Small RNAs in canine spermatogenesis, canine male infertility and contraception, Isolation and characterization of Spermatogonial Stem Cells (SSCs) in domestic animals, Characterization of boar sperm membrane and incorporation of nanolipids to increase their cryosurvival.

Female Reproduction: MicroRNAs and early embryogenesis, protein markers and early embryonic development in economically important livestock species, reproductive diseases with devastating economic consequences etc. 

Research Publications

Kasimanickam, V. and Kastelic, J. MicroRNA in sperm from Duroc, Landrace and Yorkshire boars. Sci Rep. 2016 Sep 6; 6:32954. doi: 10.1038/srep32954.

Kasimanickam VR. Expression of retinoic acid metabolizing enzymes, ALDH1A1, ALDH1A2, ALDH1A3, CYP26A1, CYP26B1 and CYP26C1 in canine testis during post-natal development. Reprod Domest Anim. 2016 Aug 28. doi: 10.1111/rda.12756. [Epub ahead of print]

Kasimanickam V, Kastelic J. Circulating cell-free mature microRNAs and their target gene prediction in bovine metritis. Sci Rep. 2016 Jul 11; 6:29509. doi: 10.1038/srep29509.

Kasimanickam VR, Kasimanickam RK, Dernell WS. Dysregulated microRNA Clusters in Response to Retinoic Acid and CYP26B1 Inhibitor Induced Testicular Function in Dogs.  PLoS One. 2014 Jun 9;9(6)

Kasimanickam V, Kasimanickam R. Exogenous Retinoic Acid and Cytochrome P450 26B1 Inhibitor Modulate Meiosis-Associated Genes Expression in Canine Testis, an In Vitro Model. Reprod Domest Anim. 2014 Jan 27.

Kasimanickam RK, Kasimanickam VR, Olsen JR, Jeffress EJ, Moore DA, Kastelic JP. Associations among serum pro- and anti-inflammatory cytokines, metabolic mediators, body condition, and uterine disease in postpartum dairy cows. Reprod Biol Endocrinol. 2013 Nov 9;11:103.

Kasimanickam RK, Ranjan A, Asokan GV, Kasimanickam VR, Kastelic JP. Prevention and treatment of biofilms by hybrid- and nanotechnologies. Int J Nanomedicine. 2013;8:2809-19.

Kasimanickam VR, Kasimanickam RK, Rogers HA. Immunolocalization of retinoic acid receptor-alpha, - beta, and -gamma, in bovine and canine sperm. Theriogenology. 2013 Apr 1;79(6):1010-8.

Kasimanickam VR, Kasimanickam RK, Kastelic JP, Stevenson JS. Associations of adiponectin and fertility estimates in Holstein bulls. Theriogenology. 2013 Mar 15;79(5):766-77.

Kasimanickam VR, Kasimanickam RK. Retinoic acid signaling biomarkers after treatment with retinoic acid and retinoic acid receptor alpha antagonist (Ro 41-5253) in canine testis: an in vitro organ culture study. Theriogenology. 2013 Jan 1;79(1):10-6. 

Kasimanickam VR, Kasimanickam RK. Expression of CYP26b1 and related retinoic acid signalling molecules in young, peripubertal and adult dog testis. Reprod Domest Anim. 2013 Feb;48(1):171-6.

PubMed Link:

Washington State University