Research Interests

Ovary Biology

Pat Hunt

Regents Professor

Room: BLS 333
Phone: 509-335-4954 Phone: 509-335-4933

Pat Hunt



List of Publications
Select Publications
  • Hrubec TC, Melin VE, Shea CS, Ferguson EE, Garofola C, Repine CM, Chapman TW, Patel HR, Razvi RM, Sugrue JE, Potineni H, Magnin-Bissel G, Hunt PA. (2017) Ambient and Dosed Exposure to Quaternary Ammonium Disinfectants Causes Neural Tube Defects in Rodents. Birth Defects Res 109(14):1166-1178 PMID: 28618200 PMCID: Article
  • Horan TS, Marre A, Hassold T, Lawson C, Hunt PA. (2017) Germline and reproductive tract effects intensify in male mice with successive generations of exposure. PLoS Genetics 13(7): e1006885 PMID: 28727826 PMCID: PMC5519010 Article
  • Hunt, PA (2017) Oocyte biology: Do the wheels fall off with age?  Dispatch in Current Biology 27(7):R266-269 PMID: 28376333 PMCID: Article
  • Wang S, Hassold T, Hunt P, White MA, Zickler D and Kleckner N (2017) Inefficient crossover maturation underlies elevated aneuploidy in human female meiosis Cell 168(6):977-989.e17 PMID: 28262352 PMCID: PMC5408880 Article
  • Ahuja JS, Sandhu R, Mainpal R, Lawson C, Henley H, Hunt PA, Yanowitz JL, Börner GV, (2017) Control of meiotic pairing and recombination by chromosomally tethered 26S proteasome. Science 355(6323):408-411 PMID: 28059715 PMCID: Article
  • VandeVoort CA, Gerona RR, vom Saal FS, Tarantal AF, Hunt PAe, Hillenweck A, Zalco D (2016) Maternal and Fetal Pharmacokinetics of Oral Radiolabeled and Authentic Bisphenol A in the Rhesus Monkey. Plos One 11(12):e0165410. PMID: 27930651 PMCID: PMC5145146 Article
  • Attina, TM, Hauser, R, Sathyanarayana, S, Hunt, PA, Bourguignon, JP, Myers, JP, DiGangi, J, Zoeller, RT, Trasande, L (2016) Exposure to endocrine-disrupting chemicals in the USA: a population-based disease burden and cost analysis. Lancet Diabetes Endocrinol 4(12):996-1003 PMID: 27765541 PMCID: Article
  • Sartain C, Hunt PA (2016) An old culprit but a new story: BPA and "NextGen” bisphenols Fertility and Sterility PMID: 27504789 PMCID: PMC5304938 Article
  • Trasande, L, Zoeller, RT, Hass, U, Kortenkamp, A, Grandjean, P, Myers, JP, DiGangi, J, Hunt, PA, Rudel, R, Sathyanarayana, S, Bellanger, M, Hauser, R, Legler, J, Skakkebaek, NE, Heindel, JJ (2016) Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis. Andrology 4(4):565-72 PMID: 27003928 PMCID: PMC5244983 Article
  • Gruhn J, Al-Asmar N, Fasnacht R, Maylor-Hagen H, Peinado V, Rubio C, Broman K, Hunt P, Hassold T (2016) Correlations between synaptic initiation and meiotic recombination: A study of humans and mice. Am J Hum Genet 98, 102-115 PMID: 26749305 PMCID: PMC4716685 Article
  • Hunt PA, Sathyanarayana S, Fowler PA, Trasande L (2016) Female Reproductive Disorders, Diseases and Costs of Exposure to Endocrine Disrupting Chemicals in the European Union. J Clin Endocrinol Metab. 101(4), 1562-70 PMID: 27003299 PMCID: PMC4880176 Article
  • Gerona RR, Pan J, Zota AR, Schwartz JM, Friesen M, Taylor JA, Hunt PA, Woodruff TJ (2016) Direct measurement of Bisphenol A (BPA), BPA glucuronide and BPA sulfate in a diverse and low-income population of pregnant women reveals high exposure, with potential implications for previous exposure estimates: a cross-sectional study. Environ Health. 15, 50 PMID: 27071747 PMCID: PMC4828888 Article
  • Vrooman L, Oatley J, Griswold J, Hassold T, Hunt P (2015) Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adult. PLoS Genet 11 PMID: 25615633 PMCID: PMC4304829 Article
  • Yang QE, Nagaoka SI, Gwost I, Hunt PA, Oatley JM (2015) Inactivation of Retinoblastoma Protein (Rb1) in the Oocyte: Evidence That Dysregulated Follicle Growth Drives Ovarian Teratoma Formation in Mice. PLoS Genet. 11(7) PMID: 26176933 PMCID: PMC4503754 Article
  • Vom Saal FS, VandeVoort CA, Taylor JA, Welshons WV, Toutain PT, Hunt PA (2014) Bisphenol A (BPA) pharmacokinetics with daily oral bolus or continuous exposure via Silastic capsules in pregnancy rhesus monkeys: Relevance for human exposures. Reprod Toxicol 45:105-116 PMID: 24582107 PMCID: PMC4035044 Article
  • Rowsey R, Gruhn J, Broman K, Hunt P, Hassold T (2014) Examining variation in recombination levels in the human female: a test of the production line hypothesis. Am J Hum Genet 95, 108-112 PMID: 24995869 PMCID: PMC4085639 Article
  • Vrooman L, Nagaoka S, Hassold T, Hunt P (2014) Evidence for paternal-age related alterations in meiotic chromosome dynamics in the mouse.      Genetics 196, 385-396 PMID: 24318536 PMCID: PMC3914612 Article
  • Baier B, Hunt P, Broman K, Hassold T (2014) Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males. PLoS Genet. 10 PMID: 24497841 PMCID: PMC3907295 Article
  • Melin VE, Potineni H, Hunt P, Griswold J, Siems B, Werre SR, Hrubec TC (2014) Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reprod Toxicol. 50, 163-70 PMID: 25483128 PMCID: PMC4260154 Article
  • Hunt PA, VandeVoort C, Woodruff T, Gerona R (2014) Invalid controls undermine conclusions of FDA studies. Toxicol Sci. PMID: 24893712 PMCID: PMC4833096 Article
  • Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA (2014) Bisphenol A and reproductive health: Update of experimental and human evidence. Environ Health Perspect. 122(8), 775-86 PMID: 24896072 PMCID: PMC4123031 Article
  • Calhoun KC, Padilla-Banks E, Jefferson WN, Liu L, Gerrish KE, Young SL, Wood CE, Hunt PA, Vandevoort CA, Williams CJ (2014) Bisphenol A exposure alters developmental gene expression in the fetal rhesus macaque uterus. PLoS One 9(1) PMID: 24465770 PMCID: PMC3900442 Article
  • Gruhn J, Rubio C, Broman K, Hunt P, Hassold T (2013) Cytological studies of human meiosis: sex-specific differences in recombination originate at, or prior to, establishment of double-strand breaks. PLoS One 8, 85075 PMID: 24376867 PMCID: PMC3869931 Article
  • Rowsey R, Kashevarova A, Murdoch B, Dickenson C, Woodruff T, Cheng E, Hunt P, Hassold T (2013) Germline mosaicism does not explain the maternal age effect on trisomy. Am J Med Genet 161, 2495-2503 PMID: 23950106 PMCID: PMC4012642 Article
  • Gerona RR, Woodruff TJ, Dickenson CA, Pan J, Schwartz JM, Sen S, Friesen MW, Fujimoto VY, Hunt PA (2013) Bisphenol-A (BPA), BPA glucuronide and BPA sulfate in mid-gestation cord serum in a northern California cohort. Environ Sci Technol. 47(21), 12477-85 PMID: 23941471 PMCID: PMC3881559 Article
  • Vandenberg LN, Hunt PA, Myers JP, Vom Saal FS (2013) Human exposures to bisphenol A: mismatches between data and assumptions. Rev Environ Health. 28(1), 37-58 PMID: 23612528 PMCID: Article
  • Murdoch B, Owen N, Stevense M, Smith H, Nagaoka S, Hassold T, McKay M, Xu H, Fu J, Revenkova E, Jessberger R, Hunt P (2013) Altered cohesin gene dosage affects Mammalian meiotic chromosome structure and behavior. PLoS Genet. 9(2) PMID: 23408896 PMCID: PMC3567145 Article